Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
| B | 0015035 | molecular_function | protein-disulfide reductase activity |
| C | 0015035 | molecular_function | protein-disulfide reductase activity |
| D | 0015035 | molecular_function | protein-disulfide reductase activity |
| E | 0015035 | molecular_function | protein-disulfide reductase activity |
| F | 0015035 | molecular_function | protein-disulfide reductase activity |
| G | 0015035 | molecular_function | protein-disulfide reductase activity |
| H | 0015035 | molecular_function | protein-disulfide reductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 601 |
| Chain | Residue |
| A | ASP33 |
| A | TYR34 |
| A | PRO36 |
| A | HOH701 |
| A | HOH765 |
| C | ARG27 |
| C | TYR34 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | GLY98 |
| B | GLY99 |
| B | ASP102 |
| B | TLA502 |
| B | HOH675 |
| B | ASN92 |
| B | GLY97 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue TLA B 502 |
| Chain | Residue |
| B | GLY99 |
| B | GLY100 |
| B | ILE189 |
| B | GOL501 |
| B | HOH657 |
| B | HOH703 |
| H | GLY98 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue TLA C 401 |
| Chain | Residue |
| A | GLY151 |
| A | HIS152 |
| C | HIS127 |
| C | HOH525 |
| C | HOH531 |
| C | HOH577 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| A | GLY155 |
| A | SER156 |
| A | GLU159 |
| C | PRO147 |
| C | ILE148 |
| C | HOH526 |
| C | HOH594 |
| C | HOH612 |
| C | HOH626 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 403 |
| Chain | Residue |
| C | ALA90 |
| C | SER186 |
| C | THR187 |
| C | TYR190 |
| C | HOH550 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 404 |
| Chain | Residue |
| A | HIS152 |
| C | ASN163 |
| C | SER167 |
| C | HOH531 |
| C | HOH540 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | PRO147 |
| D | ILE148 |
| D | HOH509 |
| D | HOH575 |
| D | HOH587 |
| D | HOH620 |
| G | SER156 |
| G | GLU159 |
| G | HOH414 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue TLA F 301 |
| Chain | Residue |
| F | TRP11 |
| F | ARG12 |
| F | LYS15 |
| F | HOH414 |
| F | HOH445 |
| F | HOH479 |
| F | HOH489 |
| H | TRP11 |
| H | ARG12 |
| H | LYS15 |
| H | HOH1380 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS F 302 |
| Chain | Residue |
| F | ALA90 |
| F | SER186 |
| F | THR187 |
| F | TYR190 |
| F | HOH436 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue TLA G 301 |
| Chain | Residue |
| D | HIS127 |
| G | GLY151 |
| G | HIS152 |
| G | HOH437 |
| G | HOH468 |
| G | HOH478 |
| G | HOH486 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue TLA H 501 |
| Chain | Residue |
| E | GLY151 |
| H | HIS127 |
| H | SER167 |
| H | LYS170 |
| H | HOH1305 |
| H | HOH1306 |
| H | HOH1310 |
| H | HOH1312 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL |
| Chain | Residue | Details |
| A | LEU-88-LEU-70 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLY77 | |
| B | PHE224 | |
| C | GLY77 | |
| C | ALA90 | |
| C | GLY97 | |
| C | ILE185 | |
| C | PHE224 | |
| D | GLY77 | |
| D | ALA90 | |
| D | GLY97 | |
| D | ILE185 | |
| A | ALA90 | |
| D | PHE224 | |
| E | GLY77 | |
| E | ALA90 | |
| E | GLY97 | |
| E | ILE185 | |
| E | PHE224 | |
| F | GLY77 | |
| F | ALA90 | |
| F | GLY97 | |
| F | ILE185 | |
| A | GLY97 | |
| F | PHE224 | |
| G | GLY77 | |
| G | ALA90 | |
| G | GLY97 | |
| G | ILE185 | |
| G | PHE224 | |
| H | GLY77 | |
| H | ALA90 | |
| H | GLY97 | |
| H | ILE185 | |
| A | ILE185 | |
| H | PHE224 | |
| A | PHE224 | |
| B | GLY77 | |
| B | ALA90 | |
| B | GLY97 | |
| B | ILE185 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:18655026 |
| Chain | Residue | Details |
| A | LYS170 | |
| F | LYS170 | |
| G | LYS170 | |
| H | LYS170 | |
| B | LYS170 | |
| C | LYS170 | |
| D | LYS170 | |
| E | LYS170 | |
