6Y6B
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 14-3-3 protein gamma | polymer | 236 | 27199.6 | 2 | UniProt (P61981) Pfam (PF00244) In PDB | Homo sapiens (Human) | Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | C, D | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 8 | 1112.2 | 2 | UniProt (Q96RR4) In PDB | Homo sapiens | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 3 | B | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol | non-polymer | 500.7 | 1 | Chemie (OD8) |
Sequence modifications
A, B: 1 - 234 (UniProt: P61981)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56623.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 500.7 | |
| All* | Total formula weight | 57124.3 |
