6Y4P
Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calmodulin-1 | polymer | 149 | 16851.6 | 1 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (Human) | |
| 2 | B (B) | Ryanodine receptor 2 | polymer | 30 | 3478.2 | 1 | UniProt (E9Q401) UniProt (by SIFTS) (Q92736) | Mus musculus (Mouse) | RyR2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,Type 2 ryanodine receptor |
| 3 | C, D, E, F (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 0 - 148 (UniProt: P0DP23)
B: 3614 - 3640 (UniProt: E9Q401)
| PDB | External Database | Details |
|---|---|---|
| Ile 53 | Asn 54 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 3611 | - | expression tag |
| Asn 3612 | - | expression tag |
| Ala 3613 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20329.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 20490.1 |
