6Y09

Crystal structure of Atg16L in complex with GTP-bound Rab33B (Q92L)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ras-related protein Rab-33B	polymer	192	21960.4	2	UniProt (Q9H082) Pfam (PF00071) In PDB	Homo sapiens (Human)
2	C, D	Autophagy-related protein 16-1	polymer	126	14532.0	2	UniProt (Q8C0J2) Pfam (PF08614) In PDB	Mus musculus (House mouse)	APG16-like 1
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
5	A, C, B, D	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
6	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
7	B	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
8		water	water		18.0	214	Chemie (HOH)

Sequence modifications

A, B: 30 - 218 (UniProt: Q9H082)

PDB	External Database	Details
Gly 27	-	expression tag
Pro 28	-	expression tag
Met 29	-	expression tag
Leu 92	Gln 92	engineered mutation

C, D: 141 - 265 (UniProt: Q8C0J2)

PDB	External Database	Details
Met 140	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	72984.8
Non-Polymers*	Number of molecules	19
	Total formula weight	2554.1
All*	Total formula weight	75538.9

*Water molecules are not included.