6Y09
Crystal structure of Atg16L in complex with GTP-bound Rab33B (Q92L)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0032482 | biological_process | Rab protein signal transduction |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0032482 | biological_process | Rab protein signal transduction |
| C | 0000045 | biological_process | autophagosome assembly |
| D | 0000045 | biological_process | autophagosome assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | THR47 |
| A | THR65 |
| A | GTP302 |
| A | HOH415 |
| A | HOH417 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue GTP A 302 |
| Chain | Residue |
| A | LYS46 |
| A | THR47 |
| A | CYS48 |
| A | THR62 |
| A | THR65 |
| A | GLY91 |
| A | ASN148 |
| A | LYS149 |
| A | ASP151 |
| A | LEU152 |
| A | SER178 |
| A | ALA179 |
| A | LYS180 |
| A | MG301 |
| A | PEG304 |
| A | HOH415 |
| A | HOH417 |
| A | HOH419 |
| A | HOH439 |
| A | HOH456 |
| A | SER42 |
| A | ASN43 |
| A | VAL44 |
| A | GLY45 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 303 |
| Chain | Residue |
| A | LYS133 |
| A | LEU136 |
| A | ALA138 |
| A | PEG306 |
| A | HOH422 |
| B | THR160 |
| B | GLU176 |
| B | ASN185 |
| B | PEG308 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 304 |
| Chain | Residue |
| A | ASP115 |
| A | THR117 |
| A | ASN118 |
| A | LYS149 |
| A | GTP302 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 305 |
| Chain | Residue |
| A | HIS123 |
| A | LEU162 |
| A | PHE166 |
| A | HOH402 |
| A | HOH414 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue PEG A 306 |
| Chain | Residue |
| A | ILE129 |
| A | CYS132 |
| A | LYS133 |
| A | LEU136 |
| A | ARG143 |
| A | PO4303 |
| A | HOH422 |
| A | HOH447 |
| B | ARG153 |
| B | ASP184 |
| B | ASN185 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 C 301 |
| Chain | Residue |
| C | GLU197 |
| D | TRP194 |
| D | GLU197 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | THR47 |
| B | THR65 |
| B | GTP302 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | binding site for residue GTP B 302 |
| Chain | Residue |
| B | SER42 |
| B | ASN43 |
| B | VAL44 |
| B | GLY45 |
| B | LYS46 |
| B | THR47 |
| B | CYS48 |
| B | THR62 |
| B | ALA64 |
| B | THR65 |
| B | GLY91 |
| B | ASN148 |
| B | LYS149 |
| B | ASP151 |
| B | LEU152 |
| B | SER178 |
| B | ALA179 |
| B | LYS180 |
| B | MG301 |
| B | HOH410 |
| B | HOH425 |
| B | HOH434 |
| B | HOH445 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 303 |
| Chain | Residue |
| A | THR160 |
| A | GLU176 |
| A | HOH410 |
| B | LYS133 |
| B | LEU136 |
| B | ALA138 |
| B | EDO304 |
| B | HOH406 |
| B | HOH460 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | CYS132 |
| B | LYS133 |
| B | LEU136 |
| B | ARG143 |
| B | PO4303 |
| B | HOH429 |
| B | HOH435 |
| A | ARG153 |
| A | ASN185 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 305 |
| Chain | Residue |
| A | THR169 |
| B | ARG52 |
| B | LYS180 |
| B | ASN181 |
| B | PRO182 |
| B | HOH474 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 306 |
| Chain | Residue |
| B | ALA120 |
| B | HIS123 |
| B | SER124 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | HIS187 |
| B | HIS170 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue PEG B 308 |
| Chain | Residue |
| A | LYS133 |
| A | GLN134 |
| A | PO4303 |
| B | LEU174 |
| B | GLU176 |
| B | ASN185 |
| B | ASP186 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 309 |
| Chain | Residue |
| B | TYR104 |
| B | ASN106 |
| B | VAL107 |
| B | LEU136 |
| B | LEU137 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 310 |
| Chain | Residue |
| B | SER127 |
| B | TRP128 |
| B | GLU131 |
| B | HOH401 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 311 |
| Chain | Residue |
| B | ASP41 |
| B | SER42 |
| B | ASN43 |
| B | VAL44 |
| B | ASP115 |
| B | ASN118 |
| B | SER121 |
| B | HOH459 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| B | ARG94 |
| C | GLU186 |
| D | GLN188 |
| D | VAL191 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"32960676","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Y09","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"32960676","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Y09","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32960676","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Y09","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32960676","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Y09","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZAY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
