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6XRE

Structure of the p53/RNA polymerase II assembly

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1970217420.01UniProt (P24928)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Homo sapiens (Human)RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1
2B
(B)
DNA-directed RNA polymerase II subunit RPB2polymer1174134071.51UniProt (P30876)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Homo sapiens (Human)DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,RNA polymerase II subunit 2,RNA polymerase II subunit B2
3C
(C)
DNA-directed RNA polymerase II subunit RPB3polymer27531478.11UniProt (P19387)
Pfam (PF01193)
Pfam (PF01000)
Homo sapiens (Human)RNA polymerase II subunit B3,DNA-directed RNA polymerase II 33 kDa polypeptide,RPB33,DNA-directed RNA polymerase II subunit C,RPB31
4D
(D)
DNA-directed RNA polymerase II subunit RPB4polymer14216331.31UniProt (O15514)
Pfam (PF03874)
Homo sapiens (Human)RNA polymerase II subunit B4,DNA-directed RNA polymerase II subunit D,RNA polymerase II 16 kDa subunit,RPB16
5E
(E)
DNA-directed RNA polymerase II subunit RPB5polymer21024584.21UniProt (P19388)
Pfam (PF03871)
Pfam (PF01191)
Homo sapiens (Human)RNA polymerases I,II,and III subunit ABC1, DNA-directed RNA DNA-directed RNA polymerases I, II, and III subunit RPABC1, polymerase II 23 kDa polypeptide, DNA-directed RNA polymerase II subunit E, XAP4
6F
(F)
DNA-directed RNA polymerases I, II, and III subunit RPABC2polymer12714491.01UniProt (P61218)
Pfam (PF01192)
Homo sapiens (Human)RNA polymerases I,II,and III subunit ABC2,DNA-directed RNA polymerase II subunit F,DNA-directed RNA polymerases I,and III 14.4 kDa polypeptide,RPABC14.4,RPB14.4,RPB6 homolog,RPC15
7G
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17219314.31UniProt (P62487)
Pfam (PF03876)
Pfam (PF00575)
Homo sapiens (Human)RNA polymerase II subunit B7,DNA-directed RNA polymerase II subunit G,RNA polymerase II 19 kDa subunit,RPB19
8H
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer15017162.31UniProt (P52434)
Pfam (PF03870)
Homo sapiens (Human)RNA polymerases I,II,and III subunit ABC3,DNA-directed RNA polymerase II subunit H,DNA-directed RNA polymerases I,and III 17.1 kDa polypeptide,RPB17,RPB8 homolog,hRPB8
9I
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12514541.21UniProt (P36954)
Pfam (PF02150)
Pfam (PF01096)
Homo sapiens (Human)RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
10J
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer677655.11UniProt (P62875)
Pfam (PF01194)
Homo sapiens (Human)RNA polymerases I,II,and III subunit ABC5,DNA-directed RNA polymerase III subunit L,RNA polymerase II 7.6 kDa subunit,RPB7.6,RPB10 homolog
11K
(K)
DNA-directed RNA polymerase II subunit RPB11-apolymer11713310.31UniProt (P52435)
Pfam (PF13656)
Homo sapiens (Human)RPB11a,DNA-directed RNA polymerase II subunit J-1,RNA polymerase II 13.3 kDa subunit
12L
(L)
DNA-directed RNA polymerases I, II, and III subunit RPABC4polymer587018.21UniProt (P53803)
Pfam (PF03604)
Homo sapiens (Human)RNA polymerases I,II,and III subunit ABC4,ABC10-alpha,DNA-directed RNA polymerase II subunit K,RNA polymerase II 7.0 kDa subunit,RPB7.0,RPB10alpha
13M
(M)
Cellular tumor antigen p53polymer39343711.21UniProt (P04637)
Pfam (PF08563)
Pfam (PF18521)
Pfam (PF00870)
Pfam (PF07710)
Homo sapiens (Human)Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
14N
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
15O, P, Q, R, S...
(A, B, C, I, L)
ZINC IONnon-polymer65.48Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight561088.8
Non-Polymers*Number of molecules9
Total formula weight547.6
All*Total formula weight561636.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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