6XQN
Structure of a mitochondrial calcium uniporter holocomplex (MICU1, MICU2, MCU, EMRE) in low Ca2+
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, G, H | Protein EMRE homolog, mitochondrial-like Protein | polymer | 70 | 7372.2 | 3 | UniProt (D6X268) Pfam (PF10161) In PDB | Tribolium castaneum (Red flour beetle) | EMRE |
2 | A, B, C, D | Calcium uniporter protein | polymer | 203 | 23634.1 | 4 | UniProt (D6WIX5) In PDB | Tribolium castaneum (Red flour beetle) | MCU |
3 | I | Calcium uptake protein 1, mitochondrial | polymer | 394 | 45422.9 | 1 | UniProt (Q9BPX6) Pfam (PF13202) In PDB | Homo sapiens (Human) | Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1, MICU1 |
4 | J | Calcium uptake protein 2, mitochondrial | polymer | 383 | 44980.6 | 1 | UniProt (Q8IYU8) In PDB | Homo sapiens (Human) | EF-hand domain-containing family member A1, MICU2 |
5 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
E, G, H: 47 - 108 (UniProt: D6X268)
A, B, C, D: 166 - 351 (UniProt: D6WIX5)
I: 94 - 476 (UniProt: Q9BPX6)
PDB | External Database | Details |
---|---|---|
Gly 39 | - | expression tag |
Pro 40 | - | expression tag |
Thr 41 | - | expression tag |
Ala 42 | - | expression tag |
Ala 43 | - | expression tag |
Ala 44 | - | expression tag |
Leu 45 | - | expression tag |
Glu 46 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 159 | - | expression tag |
Pro 160 | - | expression tag |
Thr 161 | - | expression tag |
Ala 162 | - | expression tag |
Ala 163 | - | expression tag |
Ala 164 | - | expression tag |
Leu 165 | - | expression tag |
Gly 352 | - | expression tag |
Gly 353 | - | expression tag |
Trp 354 | - | expression tag |
Ser 355 | - | expression tag |
His 356 | - | expression tag |
Pro 357 | - | expression tag |
Gln 358 | - | expression tag |
Phe 359 | - | expression tag |
Glu 360 | - | expression tag |
Lys 361 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 86 | - | expression tag |
Pro 87 | - | expression tag |
Thr 88 | - | expression tag |
Ala 89 | - | expression tag |
Ala 90 | - | expression tag |
Ala 91 | - | expression tag |
Leu 92 | - | expression tag |
Glu 93 | - | expression tag |
Ser 477 | - | expression tag |
Asn 478 | - | expression tag |
Trp 479 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 207056.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 40.1 | |
All* | Total formula weight | 207096.5 |