6XKR
Structure of Sasanlimab Fab in complex with PD-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Sasanlimab Fab Heavy chain | polymer | 231 | 24860.9 | 1 | Homo sapiens | ||
| 2 | B (L) | Sasanlimab Fab Light chain | polymer | 220 | 24372.9 | 1 | Homo sapiens | ||
| 3 | C (P) | Programmed cell death protein 1 | polymer | 141 | 15796.5 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 4 | D, E, F, G, H (H, L) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | I, J, K (H, L, P) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
P: 32 - 160 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Ser 162 | - | expression tag |
| Gly 163 | - | expression tag |
| Ser 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65030.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 65490.8 |
