6XAG
Apo BRAF dimer bound to 14-3-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein zeta/delta | polymer | 232 | 26460.9 | 2 | UniProt (P63104) Pfam (PF00244) | Homo sapiens (Human) | Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | C, D (C, D) | Serine/threonine-protein kinase B-raf | polymer | 290 | 33086.9 | 2 | UniProt (P15056) Pfam (PF07714) | Homo sapiens (Human) | Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1 |
| 3 | E (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) |
Sequence modifications
A, B: 1 - 230 (UniProt: P63104)
C, D: 447 - 735 (UniProt: P15056)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 446 | - | expression tag |
| Ala 543 | Ile 543 | conflict |
| Ser 544 | Ile 544 | conflict |
| Lys 551 | Ile 551 | conflict |
| Arg 562 | Gln 562 | conflict |
| Asn 588 | Leu 588 | conflict |
| Ser 630 | Lys 630 | conflict |
| Glu 667 | Phe 667 | conflict |
| Ser 673 | Tyr 673 | conflict |
| Arg 688 | Ala 688 | conflict |
| Ser 706 | Leu 706 | conflict |
| Arg 709 | Gln 709 | conflict |
| Glu 713 | Ser 713 | conflict |
| Glu 716 | Leu 716 | conflict |
| Glu 720 | Ser 720 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119095.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 119157.6 |
