6X3L

Sortilin-Progranulin Interaction With Compound 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Sortilin	polymer	762	84991.2	1	UniProt (Q99523) Pfam (PF15902) Pfam (PF15901) In PDB	Homo sapiens (Human)	100 kDa NT receptor,Glycoprotein 95,Gp95,Neurotensin receptor 3,NTR3
2	B, C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	A	1-benzyl-3-tert-butyl-1H-pyrazole-5-carboxylic acid	non-polymer		258.3	1	Chemie (UMJ)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: -32 - 723 (UniProt: Q99523)

PDB	External Database	Details
Met 617	Val 650	conflict
His 724	-	expression tag
His 725	-	expression tag
His 726	-	expression tag
His 727	-	expression tag
His 728	-	expression tag
His 729	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	84991.2
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	2
	Total formula weight	350.4
All*	Total formula weight	86190.4

*Water molecules are not included.