6WWH

KIF14[391-772] dimer two-heads-bound state - AMP-PNP in complex with a microtubule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (K, N)	Kinesin-like protein KIF14	polymer	390	43512.0	2	UniProt (L0N7N1) Pfam (PF00225)	Mus musculus (Mouse)
2	B, E (A, E)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain
3	C, F (B, I)	Tubulin beta-2B chain	polymer	445	49999.9	2	UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (A0A287AZ37)	Sus scrofa (Pig)
4	G, J, M, P (K, A, N, E)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	H, N (K, N)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
6	I, O (A, E)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
7	K, Q (B, I)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
8	L, R (B, I)	TAXOL	non-polymer		853.9	2	Chemie (TA1)

Sequence modifications

K, N: 391 - 772 (UniProt: L0N7N1)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	287432.7
Non-Polymers*	Number of molecules	12
	Total formula weight	4750.2
All*	Total formula weight	292182.9

*Water molecules are not included.