6WWA
Crystal structure of human SHLD2-SHLD3-REV7 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, C, B) | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 211 | 24323.3 | 4 | UniProt (Q9UI95) Pfam (PF02301) | Homo sapiens (Human) | Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7 |
| 2 | E, F (Y, X) | Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | polymer | 99 | 10678.1 | 2 | UniProt (Q86V20) UniProt (Q6ZNX1) | Homo sapiens (Human) | Protein FAM35A,RINN1-REV7-interacting novel NHEJ regulator 2,Shield complex subunit 2,REV7-interacting novel NHEJ regulator 1,Shield complex subunit 3 |
Sequence modifications
A, D, C, B: 2 - 211 (UniProt: Q9UI95)
Y, X: 2 - 16 (UniProt: Q86V20)
Y, X: 33 - 89 (UniProt: Q6ZNX1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 17 | - | linker |
| Ser 18 | - | linker |
| Gly 19 | - | linker |
| Ser 20 | - | linker |
| Gly 21 | - | linker |
| Ser 22 | - | linker |
| Gly 23 | - | linker |
| Ser 24 | - | linker |
| Gly 25 | - | linker |
| Ser 26 | - | linker |
| Gly 27 | - | linker |
| Ser 28 | - | linker |
| Gly 29 | - | linker |
| Ser 30 | - | linker |
| Gly 31 | - | linker |
| Ser 32 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 90 | - | expression tag |
| Ser 91 | - | expression tag |
| Arg 92 | - | expression tag |
| Glu 93 | - | expression tag |
| Glu 94 | - | expression tag |
| Ile 95 | - | expression tag |
| Met 96 | - | expression tag |
| Ala 97 | - | expression tag |
| Thr 98 | - | expression tag |
| Leu 99 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 118649.7 | |
| All* | Total formula weight | 118649.7 |
