6WWA

Crystal structure of human SHLD2-SHLD3-REV7 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0000785	cellular_component	chromatin
A	0001558	biological_process	regulation of cell growth
A	0002208	biological_process	somatic diversification of immunoglobulins involved in immune response
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005680	cellular_component	anaphase-promoting complex
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0005819	cellular_component	spindle
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0007015	biological_process	actin filament organization
A	0007094	biological_process	mitotic spindle assembly checkpoint signaling
A	0008432	molecular_function	JUN kinase binding
A	0010717	biological_process	regulation of epithelial to mesenchymal transition
A	0010719	biological_process	negative regulation of epithelial to mesenchymal transition
A	0010944	biological_process	negative regulation of transcription by competitive promoter binding
A	0016035	cellular_component	zeta DNA polymerase complex
A	0019985	biological_process	translesion synthesis
A	0030674	molecular_function	protein-macromolecule adaptor activity
A	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
A	0035861	cellular_component	site of double-strand break
A	0042177	biological_process	negative regulation of protein catabolic process
A	0042276	biological_process	error-prone translesion synthesis
A	0042772	biological_process	DNA damage response, signal transduction resulting in transcription
A	0043247	biological_process	telomere maintenance in response to DNA damage
A	0045830	biological_process	positive regulation of isotype switching
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0051301	biological_process	cell division
A	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
A	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
A	0090734	cellular_component	site of DNA damage
A	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
A	2000042	biological_process	negative regulation of double-strand break repair via homologous recombination
A	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
A	2001034	biological_process	positive regulation of double-strand break repair via nonhomologous end joining
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0000785	cellular_component	chromatin
B	0001558	biological_process	regulation of cell growth
B	0002208	biological_process	somatic diversification of immunoglobulins involved in immune response
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005680	cellular_component	anaphase-promoting complex
B	0005694	cellular_component	chromosome
B	0005737	cellular_component	cytoplasm
B	0005819	cellular_component	spindle
B	0006281	biological_process	DNA repair
B	0006302	biological_process	double-strand break repair
B	0006974	biological_process	DNA damage response
B	0007015	biological_process	actin filament organization
B	0007094	biological_process	mitotic spindle assembly checkpoint signaling
B	0008432	molecular_function	JUN kinase binding
B	0010717	biological_process	regulation of epithelial to mesenchymal transition
B	0010719	biological_process	negative regulation of epithelial to mesenchymal transition
B	0010944	biological_process	negative regulation of transcription by competitive promoter binding
B	0016035	cellular_component	zeta DNA polymerase complex
B	0019985	biological_process	translesion synthesis
B	0030674	molecular_function	protein-macromolecule adaptor activity
B	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
B	0035861	cellular_component	site of double-strand break
B	0042177	biological_process	negative regulation of protein catabolic process
B	0042276	biological_process	error-prone translesion synthesis
B	0042772	biological_process	DNA damage response, signal transduction resulting in transcription
B	0043247	biological_process	telomere maintenance in response to DNA damage
B	0045830	biological_process	positive regulation of isotype switching
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0051301	biological_process	cell division
B	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
B	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
B	0090734	cellular_component	site of DNA damage
B	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
B	2000042	biological_process	negative regulation of double-strand break repair via homologous recombination
B	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
B	2001034	biological_process	positive regulation of double-strand break repair via nonhomologous end joining
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0000785	cellular_component	chromatin
C	0001558	biological_process	regulation of cell growth
C	0002208	biological_process	somatic diversification of immunoglobulins involved in immune response
C	0003714	molecular_function	transcription corepressor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005680	cellular_component	anaphase-promoting complex
C	0005694	cellular_component	chromosome
C	0005737	cellular_component	cytoplasm
C	0005819	cellular_component	spindle
C	0006281	biological_process	DNA repair
C	0006302	biological_process	double-strand break repair
C	0006974	biological_process	DNA damage response
C	0007015	biological_process	actin filament organization
C	0007094	biological_process	mitotic spindle assembly checkpoint signaling
C	0008432	molecular_function	JUN kinase binding
C	0010717	biological_process	regulation of epithelial to mesenchymal transition
C	0010719	biological_process	negative regulation of epithelial to mesenchymal transition
C	0010944	biological_process	negative regulation of transcription by competitive promoter binding
C	0016035	cellular_component	zeta DNA polymerase complex
C	0019985	biological_process	translesion synthesis
C	0030674	molecular_function	protein-macromolecule adaptor activity
C	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
C	0035861	cellular_component	site of double-strand break
C	0042177	biological_process	negative regulation of protein catabolic process
C	0042276	biological_process	error-prone translesion synthesis
C	0042772	biological_process	DNA damage response, signal transduction resulting in transcription
C	0043247	biological_process	telomere maintenance in response to DNA damage
C	0045830	biological_process	positive regulation of isotype switching
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0051301	biological_process	cell division
C	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
C	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
C	0090734	cellular_component	site of DNA damage
C	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
C	2000042	biological_process	negative regulation of double-strand break repair via homologous recombination
C	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
C	2001034	biological_process	positive regulation of double-strand break repair via nonhomologous end joining
D	0000122	biological_process	negative regulation of transcription by RNA polymerase II
D	0000785	cellular_component	chromatin
D	0001558	biological_process	regulation of cell growth
D	0002208	biological_process	somatic diversification of immunoglobulins involved in immune response
D	0003714	molecular_function	transcription corepressor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005680	cellular_component	anaphase-promoting complex
D	0005694	cellular_component	chromosome
D	0005737	cellular_component	cytoplasm
D	0005819	cellular_component	spindle
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006974	biological_process	DNA damage response
D	0007015	biological_process	actin filament organization
D	0007094	biological_process	mitotic spindle assembly checkpoint signaling
D	0008432	molecular_function	JUN kinase binding
D	0010717	biological_process	regulation of epithelial to mesenchymal transition
D	0010719	biological_process	negative regulation of epithelial to mesenchymal transition
D	0010944	biological_process	negative regulation of transcription by competitive promoter binding
D	0016035	cellular_component	zeta DNA polymerase complex
D	0019985	biological_process	translesion synthesis
D	0030674	molecular_function	protein-macromolecule adaptor activity
D	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
D	0035861	cellular_component	site of double-strand break
D	0042177	biological_process	negative regulation of protein catabolic process
D	0042276	biological_process	error-prone translesion synthesis
D	0042772	biological_process	DNA damage response, signal transduction resulting in transcription
D	0043247	biological_process	telomere maintenance in response to DNA damage
D	0045830	biological_process	positive regulation of isotype switching
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0051301	biological_process	cell division
D	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
D	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
D	0090734	cellular_component	site of DNA damage
D	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
D	2000042	biological_process	negative regulation of double-strand break repair via homologous recombination
D	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
D	2001034	biological_process	positive regulation of double-strand break repair via nonhomologous end joining
X	0010569	biological_process	regulation of double-strand break repair via homologous recombination
Y	0010569	biological_process	regulation of double-strand break repair via homologous recombination