6WJG

PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion	polymer	405	47338.0	2	UniProt (P25685) UniProt (P17612) Pfam (PF00226) Pfam (PF00069) In PDB	Homo sapiens (Human)	DnaJ protein homolog 1,Heat shock 40 kDa protein 1,Heat shock protein 40,Human DnaJ protein 1,hDj-1,PKA C-alpha
2	C, D	cAMP-dependent protein kinase type II-beta regulatory subunit	polymer	416	46177.9	2	UniProt (P12369) Pfam (PF02197) Pfam (PF00027) In PDB	Rattus norvegicus (Rat)

Sequence modifications

A, B: 1 - 69 (UniProt: P25685)
A, B: 70 - 405 (UniProt: P17612)

PDB	External Database	Details
Gly 273	Ala 211	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	187031.7
All*	Total formula weight	187031.7

*Water molecules are not included.