6WJC

Muscarinic acetylcholine receptor 1 - muscarinic toxin 7 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Muscarinic acetylcholine receptor M1,Endolysin fusion	polymer	499	56907.2	1	UniProt (P11229) UniProt (D9IEF7) Pfam (PF00001)	Homo sapiens (Human)	Lysis protein,Lysozyme,Muramidase
2	B (C)	Muscarinic toxin 7	polymer	69	7787.9	1	UniProt (Q8QGR0)	Dendroaspis angusticeps (Eastern green mamba)	MT7,Muscarinic toxin 1,m1-toxin
3	C (A)	ACETAMIDE	non-polymer		59.1	1	Chemie (ACM)
4	D, E, F, G (A)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	4	Chemie (Y01)
5	H (A)	(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE	non-polymer		289.4	1	Chemie (OIN)
6	I, J (A, C)	water	water		18.0	7	Chemie (HOH)

Sequence modifications

A: 2 - 218 (UniProt: P11229)

PDB	External Database	Details
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag
Ala 1	-	expression tag
Gln 2	Asn 2	conflict
Gln 12	Asn 12	conflict
Gln 110	Asn 110	conflict
Arg 112	Ser 112	conflict

A: 1001 - 1160 (UniProt: D9IEF7)

PDB	External Database	Details
Thr 1053	Cys 54	conflict
Ala 1096	Cys 97	conflict

A: 355 - 460 (UniProt: P11229)

PDB	External Database	Details
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag

C: 1 - 65 (UniProt: Q8QGR0)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64695.0
Non-Polymers*	Number of molecules	6
	Total formula weight	2295.3
All*	Total formula weight	66990.4

*Water molecules are not included.