6WH9
Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 1D10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, H, I (G, D, A) | KR1 | polymer | 485 | 50889.0 | 3 | UniProt (Q5UNP6) Pfam (PF08659) UniProt (by SIFTS) (Q03131) | Saccharopolyspora erythraea | 6-deoxyerythronolide B synthase |
| 2 | B, D, F (E, B, H) | 1D10 (Fab heavy chain) | polymer | 246 | 26135.0 | 3 | Homo sapiens (Human) | ||
| 3 | C, E, G (F, C, I) | 1D10 (Fab light chain) | polymer | 231 | 24516.5 | 3 | Homo sapiens (Human) | ||
| 4 | J, K, L, M, N... (G, E, F, B, C...) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 5 | Q, R, S, T, U... (G, E, F, B, C...) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
G, D, A: 1448 - 1928 (UniProt: Q5UNP6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1444 | - | expression tag |
| Ser 1445 | - | expression tag |
| His 1446 | - | expression tag |
| Met 1447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 304621.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 672.4 | |
| All* | Total formula weight | 305293.7 |
