6WCW
Structure of human Rubicon RH domain in complex with GTP-bound Rab7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Ras-related protein Rab-7a | polymer | 184 | 20840.7 | 1 | UniProt (P51149) Pfam (PF00071) In PDB | Homo sapiens (Human) | |
| 2 | A | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein | polymer | 254 | 29541.4 | 1 | UniProt (Q92622) Pfam (PF13901) In PDB | Homo sapiens (Human) | Rubicon, Beclin-1 associated RUN domain containing protein,Baron |
| 3 | B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 4 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
B: 2 - 182 (UniProt: P51149)
A: 699 - 949 (UniProt: Q92622)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Leu 67 | Gln 67 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 696 | - | expression tag |
| Asn 697 | - | expression tag |
| Ala 698 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50382.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 809.1 | |
| All* | Total formula weight | 51191.3 |
