6WC5
Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Myocyte-specific enhancer factor 2B | polymer | 90 | 10737.5 | 4 | UniProt (Q02080) Pfam (PF00319) | Homo sapiens (Human) | RSRFR2,Serum response factor-like protein 2 |
| 2 | E, G (E, G) | Myocardin enhancer DNA | polymer | 22 | 6774.4 | 2 | synthetic construct | ||
| 3 | F, H (F, H) | Myocardin enhancer DNA | polymer | 22 | 6725.4 | 2 | synthetic construct | ||
| 4 | I, J (I, N) | Homeobox protein Nkx-2.5 | polymer | 57 | 7043.1 | 2 | UniProt (P52952) Pfam (PF00046) | Homo sapiens (Human) | Cardiac-specific homeobox,Homeobox protein CSX,Homeobox protein NK-2 homolog E |
| 5 | K, L, M (C, D, F) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
I, N: 140 - 196 (UniProt: P52952)
| PDB | External Database | Details |
|---|---|---|
| Ser 193 | Cys 193 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 84035.7 | |
| All* | Total formula weight | 84035.7 |
