6WBM
Cryo-EM structure of human Pannexin 1 channel N255A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pannexin-1 | polymer | 373 | 42204.4 | 7 | UniProt (Q96RD7) Pfam (PF00876) | Homo sapiens (Human) | |
| 2 | AA, BA, GA, H, HA... (D, E, A, F, B...) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 14 | Chemie (PTY) | |||
| 3 | CA, IA, J, OA, Q... (D, E, A, F, B...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 7 | Chemie (3PE) | |||
| 4 | FA, K, LA, N, RA... (D, A, E, F, B...) | DIACYL GLYCEROL | non-polymer | 625.0 | 7 | Chemie (DGA) | |||
| 5 | DA, EA, JA, KA, L... (D, E, A, F, B...) | CHOLESTEROL | non-polymer | 386.7 | 14 | Chemie (CLR) |
Sequence modifications
A, B, C, D, E, F, G: 1 - 373 (UniProt: Q96RD7)
| PDB | External Database | Details |
|---|---|---|
| Ala 255 | Asn 255 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 295430.9 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 25301.3 | |
| All* | Total formula weight | 320732.2 |
