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6WBG

Cryo-EM structure of human Pannexin 1 channel with its C-terminal tail cleaved by caspase-7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Pannexin-1polymer37342247.47UniProt (Q96RD7)
Pfam (PF00876)
Homo sapiens (Human)
2CA, DA, H, I, JA...
(D, A, E, B, F...)
PHOSPHATIDYLETHANOLAMINEnon-polymer734.014Chemie (PTY)
3EA, J, LA, Q, SA...
(D, A, E, B, F...)
1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.17Chemie (3PE)
4AB, FA, K, MA, R...
(G, D, A, E, B...)
DIACYL GLYCEROLnon-polymer625.07Chemie (DGA)
5AA, BB, CB, GA, HA...
(C, G, D, A, E...)
CHOLESTEROLnon-polymer386.714Chemie (CLR)
6BA, DB, IA, N, PA...
(C, G, D, A, E...)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.27Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight295732.1
Non-Polymers*Number of molecules49
Total formula weight26849.7
All*Total formula weight322581.8
*Water molecules are not included.

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PDB entries from 2025-07-23

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