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6W8W

Crystal structure of mouse DNMT1 in complex with CCG DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDNA (cytosine-5)-methyltransferase 1polymer87398980.62UniProt (P13864)
Pfam (PF01426)
Pfam (PF00145)
In PDB
Mus musculus (Mouse)Met-1,DNA methyltransferase MmuI,M.MmuI,MCMT
2C, ECCG DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3')polymer123725.52synthetic construct
3D, FCCG DNA (5'-D(*CP*CP*TP*TP*CP*(C49)P*GP*TP*AP*AP*GP*T)-3')polymer123677.42synthetic construct
4A, BS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
5A, BZINC IONnon-polymer65.44Chemie (ZN)
6waterwater18.062Chemie (HOH)
Sequence modifications
A, B: 731 - 1602 (UniProt: P13864)
PDBExternal DatabaseDetails
Ser 730-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight212766.9
Non-Polymers*Number of molecules6
Total formula weight1030.5
All*Total formula weight213797.4
*Water molecules are not included.

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PDB entries from 2024-05-01

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