Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003682 | molecular_function | chromatin binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| B | 0003682 | molecular_function | chromatin binding |
| B | 0008168 | molecular_function | methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue SAH A 1701 |
| Chain | Residue |
| A | PHE1148 |
| A | ASP1193 |
| A | CYS1194 |
| A | GLY1226 |
| A | LEU1250 |
| A | ASN1580 |
| A | ALA1581 |
| A | VAL1582 |
| D | C4918 |
| A | SER1149 |
| A | GLY1150 |
| A | GLY1152 |
| A | GLY1153 |
| A | LEU1154 |
| A | GLU1171 |
| A | MET1172 |
| A | TRP1173 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 1702 |
| Chain | Residue |
| A | CYS1479 |
| A | CYS1481 |
| A | CYS1487 |
| A | HIS1504 |
| A | HOH1811 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1703 |
| Chain | Residue |
| A | HIS796 |
| A | CYS823 |
| A | CYS897 |
| A | CYS900 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue SAH B 1701 |
| Chain | Residue |
| B | PHE1148 |
| B | SER1149 |
| B | GLY1150 |
| B | GLY1152 |
| B | GLY1153 |
| B | LEU1154 |
| B | ILE1170 |
| B | GLU1171 |
| B | MET1172 |
| B | TRP1173 |
| B | ASP1193 |
| B | CYS1194 |
| B | GLY1226 |
| B | ASN1580 |
| B | ALA1581 |
| B | VAL1582 |
| F | C4918 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1702 |
| Chain | Residue |
| B | CYS1479 |
| B | CYS1481 |
| B | CYS1487 |
| B | HIS1504 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1703 |
| Chain | Residue |
| B | HIS796 |
| B | CYS823 |
| B | CYS897 |
| B | CYS900 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for Di-nucleotide DC D 17 and C49 D 18 |
| Chain | Residue |
| A | LYS985 |
| A | GLY1226 |
| A | PRO1227 |
| A | PRO1228 |
| A | CYS1229 |
| A | SER1233 |
| A | MET1235 |
| A | GLU1269 |
| A | VAL1271 |
| A | THR1312 |
| A | ARG1313 |
| A | ARG1314 |
| A | ARG1315 |
| A | THR1527 |
| A | GLY1579 |
| A | ASN1580 |
| A | SAH1701 |
| D | DT16 |
| D | DG19 |
| site_id | AC8 |
| Number of Residues | 23 |
| Details | binding site for Di-nucleotide C49 D 18 and DG D 19 |
| Chain | Residue |
| A | GLY1226 |
| A | PRO1227 |
| A | PRO1228 |
| A | CYS1229 |
| A | GLN1230 |
| A | SER1233 |
| A | MET1235 |
| A | ASN1236 |
| A | ARG1237 |
| A | GLU1269 |
| A | VAL1271 |
| A | ARG1313 |
| A | ARG1315 |
| A | THR1530 |
| A | GLY1536 |
| A | LYS1537 |
| A | GLY1579 |
| A | ASN1580 |
| A | SAH1701 |
| C | DA5 |
| C | 5CM6 |
| D | DC17 |
| D | DT20 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for Di-nucleotide DA E 5 and 5CM E 6 |
| Chain | Residue |
| B | TRP1512 |
| B | MET1535 |
| E | DT4 |
| E | DG7 |
| F | DG19 |
| F | DT20 |
| F | DA21 |
| B | ARG1237 |
| B | ARG1492 |
| B | CYS1501 |
| B | HIS1504 |
| B | THR1505 |
| B | HIS1509 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for Di-nucleotide 5CM E 6 and DG E 7 |
| Chain | Residue |
| B | GLY1234 |
| B | MET1235 |
| B | ASN1236 |
| B | ARG1237 |
| B | CYS1501 |
| B | HIS1504 |
| B | THR1505 |
| B | ARG1508 |
| B | HIS1509 |
| B | TRP1512 |
| B | MET1535 |
| E | DA5 |
| E | DG8 |
| F | DG19 |
| site_id | AD2 |
| Number of Residues | 17 |
| Details | binding site for Di-nucleotide DC F 17 and C49 F 18 |
| Chain | Residue |
| B | LYS985 |
| B | GLY1226 |
| B | PRO1227 |
| B | PRO1228 |
| B | CYS1229 |
| B | SER1233 |
| B | MET1235 |
| B | GLU1269 |
| B | VAL1271 |
| B | ARG1313 |
| B | ARG1314 |
| B | ARG1315 |
| B | THR1527 |
| B | ASN1580 |
| B | SAH1701 |
| F | DT16 |
| F | DG19 |
| site_id | AD3 |
| Number of Residues | 20 |
| Details | binding site for Di-nucleotide C49 F 18 and DG F 19 |
| Chain | Residue |
| B | GLY1226 |
| B | PRO1227 |
| B | PRO1228 |
| B | CYS1229 |
| B | SER1233 |
| B | MET1235 |
| B | ARG1237 |
| B | GLU1269 |
| B | VAL1271 |
| B | ARG1313 |
| B | ARG1315 |
| B | THR1530 |
| B | GLY1536 |
| B | LYS1537 |
| B | ASN1580 |
| B | SAH1701 |
| E | DA5 |
| E | 5CM6 |
| F | DC17 |
| F | DT20 |
Functional Information from PROSITE/UniProt
| site_id | PS00094 |
| Number of Residues | 13 |
| Details | C5_MTASE_1 C-5 cytosine-specific DNA methylases active site. EmLcgGpPCqGFS |
| Chain | Residue | Details |
| A | GLU1221-SER1233 | |
| site_id | PS00095 |
| Number of Residues | 19 |
| Details | C5_MTASE_2 C-5 cytosine-specific DNA methylases C-terminal signature. RqvGNAVpPpLakaIgleI |
| Chain | Residue | Details |
| A | ARG1576-ILE1594 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS1229 | |
| B | CYS1229 | |
| Chain | Residue | Details |
| A | SER1149 | |
| B | SER1149 | |
| Chain | Residue | Details |
| A | GLY1153 | |
| A | GLU1171 | |
| A | VAL1582 | |
| B | GLY1153 | |
| B | GLU1171 | |
| B | VAL1582 | |
| Chain | Residue | Details |
| A | ASP1193 | |
| B | ASP1193 | |
| Chain | Residue | Details |
| A | SER735 | |
| A | SER882 | |
| B | SER735 | |
| B | SER882 | |
| Chain | Residue | Details |
| A | LYS752 | |
| A | LYS1352 | |
| A | LYS1418 | |
| B | LYS752 | |
| B | LYS895 | |
| B | LYS961 | |
| B | LYS965 | |
| B | LYS979 | |
| B | LYS1114 | |
| B | LYS1116 | |
| B | LYS1118 | |
| A | LYS895 | |
| B | LYS1120 | |
| B | LYS1352 | |
| B | LYS1418 | |
| A | LYS961 | |
| A | LYS965 | |
| A | LYS979 | |
| A | LYS1114 | |
| A | LYS1116 | |
| A | LYS1118 | |
| A | LYS1120 | |
| Chain | Residue | Details |
| A | LYS1122 | |
| A | LYS1124 | |
| B | LYS1122 | |
| B | LYS1124 | |
