6W8V
Crystal structure of mouse DNMT1 in complex with ACG DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA (cytosine-5)-methyltransferase 1 | polymer | 873 | 98980.6 | 2 | UniProt (P13864) Pfam (PF01426) Pfam (PF00145) | Mus musculus (Mouse) | Met-1,DNA methyltransferase MmuI,M.MmuI,MCMT |
| 2 | C, D (C, E) | ACG DNA (5'-D(*CP*CP*TP*TP*CP*(5CM)P*GP*TP*AP*AP*GP*T)-3') | polymer | 12 | 3627.4 | 2 | synthetic construct | ||
| 3 | E, F (D, F) | ACG DNA (5'-D(*AP*CP*TP*TP*AP*(C49)P*GP*GP*AP*AP*GP*G)-3') | polymer | 12 | 3775.5 | 2 | synthetic construct | ||
| 4 | G, J (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | H, I, K, L (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, B: 731 - 1602 (UniProt: P13864)
| PDB | External Database | Details |
|---|---|---|
| Ser 730 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 212766.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1030.5 | |
| All* | Total formula weight | 213797.4 |
