6W65
Human PARP16 in complex with RBN010860
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Protein mono-ADP-ribosyltransferase PARP16 | polymer | 277 | 31110.6 | 3 | UniProt (Q8N5Y8) Pfam (PF18084) Pfam (PF00644) | Homo sapiens (Human) | ADP-ribosyltransferase diphtheria toxin-like 15,Poly [ADP-ribose] polymerase 16,PARP-16 |
| 2 | D, K, U (A, B, C) | 5-{5-[(piperidin-4-yl)oxy]-2H-isoindol-2-yl}-4-(trifluoromethyl)pyridazin-3(2H)-one | non-polymer | 378.3 | 3 | Chemie (T9D) | |||
| 3 | E, L (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | F, G, H, I, M... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 5 | J, S, T, X (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | R, W (B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | AA, Y, Z (C, A, B) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A, B, C: 5 - 279 (UniProt: Q8N5Y8)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | expression tag |
| Met 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93331.7 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2900.7 | |
| All* | Total formula weight | 96232.5 |
