Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003950 | molecular_function | NAD+ poly-ADP-ribosyltransferase activity |
| B | 0003950 | molecular_function | NAD+ poly-ADP-ribosyltransferase activity |
| C | 0003950 | molecular_function | NAD+ poly-ADP-ribosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue T9D A 301 |
| Chain | Residue |
| A | PHE151 |
| A | TYR254 |
| A | HOH418 |
| A | HOH518 |
| B | ARG49 |
| A | HIS152 |
| A | GLY153 |
| A | TYR182 |
| A | LEU183 |
| A | THR184 |
| A | LEU189 |
| A | ALA190 |
| A | TYR193 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue CIT A 302 |
| Chain | Residue |
| A | HIS152 |
| A | SER154 |
| A | ASN158 |
| A | LEU167 |
| A | HIS168 |
| A | HIS170 |
| A | HOH405 |
| A | HOH418 |
| A | HOH450 |
| A | HOH467 |
| A | HOH497 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ALA12 |
| A | ARG15 |
| A | ASP16 |
| A | THR96 |
| A | ILE97 |
| A | HIS98 |
| C | HOH427 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | SER33 |
| A | TYR34 |
| A | GLU157 |
| A | HOH420 |
| A | HOH485 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | MET4 |
| A | SER92 |
| A | GOL306 |
| C | ASP132 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | SER92 |
| A | LYS93 |
| A | PHE131 |
| A | GOL305 |
| C | PHE131 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | ASN67 |
| A | HIS202 |
| A | HOH475 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue T9D B 301 |
| Chain | Residue |
| B | PHE151 |
| B | HIS152 |
| B | GLY153 |
| B | TYR182 |
| B | LEU183 |
| B | THR184 |
| B | LEU189 |
| B | ALA190 |
| B | TYR193 |
| B | TYR254 |
| B | CIT302 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CIT B 302 |
| Chain | Residue |
| B | HIS152 |
| B | GLY153 |
| B | SER154 |
| B | HIS168 |
| B | T9D301 |
| B | HOH447 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | ARG15 |
| B | SER74 |
| B | SER75 |
| B | GLY76 |
| B | ASP77 |
| B | ASN78 |
| B | HIS79 |
| B | LYS80 |
| B | TRP83 |
| B | EDO310 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| B | ARG23 |
| B | TRP88 |
| B | ILE89 |
| B | SER91 |
| B | SER92 |
| B | HIS164 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 305 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 306 |
| Chain | Residue |
| B | ASN67 |
| B | HIS202 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 307 |
| Chain | Residue |
| B | ASN78 |
| B | HIS79 |
| B | LYS80 |
| B | ARG81 |
| B | ALA82 |
| B | HOH429 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 308 |
| Chain | Residue |
| B | GLN32 |
| B | ARG36 |
| C | ARG36 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| B | SER33 |
| B | TYR34 |
| B | GLU157 |
| C | ASP54 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | ARG10 |
| B | GLU11 |
| B | ARG15 |
| B | TRP83 |
| B | GOL303 |
| B | TRP6 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue T9D C 301 |
| Chain | Residue |
| C | PHE151 |
| C | HIS152 |
| C | GLY153 |
| C | TYR182 |
| C | LEU183 |
| C | THR184 |
| C | ALA190 |
| C | TYR193 |
| C | TYR254 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| C | HIS152 |
| C | SER154 |
| C | ILE162 |
| C | HIS168 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue PEG C 303 |
| Chain | Residue |
| C | ARG15 |
| C | ASP16 |
| C | THR96 |
| C | ILE97 |
| C | HIS98 |
| C | HOH444 |
| C | HOH450 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 304 |
| Chain | Residue |
| C | PHE105 |
| C | PRO122 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 172 |
| Details | Domain: {"description":"PARP alpha-helical"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22661712","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Site: {"description":"Nicotinamide-stacking aromate","evidences":[{"source":"PubMed","id":"22661712","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"ADP-ribosyl aspartic acid","evidences":[{"source":"PubMed","id":"25043379","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"ADP-ribosyl glutamic acid","evidences":[{"source":"PubMed","id":"25043379","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-(ADP-ribosyl)lysine","evidences":[{"source":"PubMed","id":"25043379","evidenceCode":"ECO:0000269"}]} |
