6W4R
Structure of Tdp1 catalytic domain in complex with inhibitor XZ633p
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosyl-DNA phosphodiesterase 1 | polymer | 461 | 52126.3 | 2 | UniProt (Q9NUW8) Pfam (PF06087) | Homo sapiens (Human) | Tyr-DNA phosphodiesterase 1 |
| 2 | C (A) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 1 | Chemie (MPO) | |||
| 3 | D, G (A, B) | 4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}benzene-1,2-dicarboxylic acid | non-polymer | 390.3 | 2 | Chemie (SZV) | |||
| 4 | E, F, H, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 698 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104252.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1300.3 | |
| All* | Total formula weight | 105553.0 |
