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6W10

Structure of mouse TREX1 with E198K disease-associated mutation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Three-prime repair exonuclease 1polymer24326411.12UniProt (Q91XB0)Mus musculus (Mouse)3'-5' exonuclease TREX1
2C, D
(A, B)
waterwater18.0483Chemie (HOH)
Sequence modifications
A, B: 1 - 242 (UniProt: Q91XB0)
PDBExternal DatabaseDetails
Ser 0-expression tag
Lys 198Glu 198engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight52822.2
All*Total formula weight52822.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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