6VZR
Engineered TTLL6 bound to the initiation analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tubulin polyglutamylase TTLL6 | polymer | 453 | 53345.4 | 4 | UniProt (A4Q9E8) Pfam (PF03133) | Mus musculus (Mouse) | Tubulin--tyrosine ligase-like protein 6 |
| 2 | E (F) | TTLL6 unregistered chain | polymer | 12 | 1039.3 | 1 | Mus musculus (Mouse) | ||
| 3 | F (G) | TTLL6 unregistered chain | polymer | 11 | 954.2 | 1 | Mus musculus (Mouse) | ||
| 4 | DA, G, QA, S (C, A, D, B) | (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid | non-polymer | 460.3 | 4 | Chemie (2TI) | |||
| 5 | EA, H, RA, T (C, A, D, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 6 | AA, BA, CA, FA, GA... (B, C, A, D) | GLYCEROL | non-polymer | 92.1 | 26 | Chemie (GOL) | |||
| 7 | KA, LA, P, Q, TA... (C, A, D, B) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 8 | WA, XA, YA, ZA (A, B, C, D) | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 51 - 503 (UniProt: A4Q9E8)
| PDB | External Database | Details |
|---|---|---|
| Ala 179 | Cys 179 | engineered mutation |
| Arg 180 | Gln 180 | engineered mutation |
| Ile 362 | His 362 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 215375.0 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 6138.9 | |
| All* | Total formula weight | 221514.0 |
