6VZR
Engineered TTLL6 bound to the initiation analog
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Tubulin polyglutamylase TTLL6 | polymer | 453 | 53345.4 | 4 | UniProt (A4Q9E8) Pfam (PF03133) In PDB | Mus musculus (Mouse) | Tubulin--tyrosine ligase-like protein 6 |
2 | F | TTLL6 unregistered chain | polymer | 12 | 1039.3 | 1 | Mus musculus (Mouse) | ||
3 | G | TTLL6 unregistered chain | polymer | 11 | 954.2 | 1 | Mus musculus (Mouse) | ||
4 | C, A, D, B | (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid | non-polymer | 460.3 | 4 | Chemie (2TI) | |||
5 | C, A, D, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
6 | B, C, A, D | GLYCEROL | non-polymer | 92.1 | 26 | Chemie (GOL) | |||
7 | C, A, D, B | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
8 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 51 - 503 (UniProt: A4Q9E8)
PDB | External Database | Details |
---|---|---|
Ala 179 | Cys 179 | engineered mutation |
Arg 180 | Gln 180 | engineered mutation |
Ile 362 | His 362 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 215375.0 | |
Non-Polymers* | Number of molecules | 42 |
Total formula weight | 6138.9 | |
All* | Total formula weight | 221514.0 |