6VTT
Cryo-EM Structure of CAP256-VRC26.25 Fab bound to HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (F, E, G) | Envelope glycoprotein gp120 | polymer | 471 | 53322.4 | 3 | Pfam (PF00516) UniProt (by SIFTS) (A0A0N9FF17) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | D (H) | VRC26.25 Heavy Chain | polymer | 257 | 28083.5 | 1 | Homo sapiens (Human) | ||
| 3 | E (L) | VRC26.25 Light Chain | polymer | 217 | 23052.6 | 1 | UniProt (A2NUT2) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 4 | F, G, H (A, B, C) | Envelope glycoprotein gp41 | polymer | 154 | 17355.7 | 3 | Human immunodeficiency virus 1 (HIV-1) | ||
| 5 | AA, CA, DA, I, J... (a, c, d, D, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
| 6 | L, X (K, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | O, W (O, W) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 8 | T (T) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 9 | V (V) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 10 | BA (b) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 11 | AB, BB, CB, DB, EA... (E, G, F, A, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 41 | Chemie (NAG) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 263170.5 | |
| Branched | Number of molecules | 22 |
| Total formula weight | 12255.4 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 9069.5 | |
| All* | Total formula weight | 284495.4 |
