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6VNO

Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leucine-rich repeat serine/threonine-protein kinase 2polymer1201136943.61UniProt (Q5S007)
Pfam (PF08477)
Pfam (PF16095)
Pfam (PF00069)
Homo sapiens (Human)Dardarin
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight136943.6
Non-Polymers*Number of molecules2
Total formula weight467.5
All*Total formula weight137411.1
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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