6VMJ
Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, E, I, L) | Fab20D12 Light Chain | polymer | 214 | 23360.8 | 4 | Homo sapiens | ||
| 2 | B, D, F, H (B, F, J, M) | Fab20D12 heavy chain | polymer | 223 | 23668.4 | 4 | Homo sapiens | ||
| 3 | I, J, K, L (W, X, Y, Z) | Complement factor D | polymer | 228 | 24438.8 | 4 | UniProt (P00746) Pfam (PF00089) | Homo sapiens (Human) | Adipsin,C3 convertase activator,Properdin factor D |
| 4 | M, N, O, P, Q... (B, F, J, M, W...) | CITRIC ACID | non-polymer | 192.1 | 6 | Chemie (CIT) | |||
| 5 | AA, BA, CA, S, T... (X, Y, Z, A, E...) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 285871.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1152.7 | |
| All* | Total formula weight | 287024.7 |
