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6VMJ

Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E, I, LFab20D12 Light Chainpolymer21423360.84Homo sapiens
2B, F, J, MFab20D12 heavy chainpolymer22323668.44Homo sapiens
3W, X, Y, ZComplement factor Dpolymer22824438.84UniProt (P00746)
Pfam (PF00089)
In PDB
Homo sapiens (Human)Adipsin,C3 convertase activator,Properdin factor D
4B, F, J, M, W...CITRIC ACIDnon-polymer192.16Chemie (CIT)
5waterwater18.0151Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight285871.9
Non-Polymers*Number of molecules6
Total formula weight1152.7
All*Total formula weight287024.7
*Water molecules are not included.

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PDB entries from 2024-06-12

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