Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6VLM

Core Catalytic Domain of HIV Integrase in complex with virtual screening hit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BIntegrasepolymer17719515.22UniProt (A0A0U2U525)
Pfam (PF00665)
UniProt (by SIFTS) (P03367)
In PDB
Human immunodeficiency virus 1
2A, B[3-(4-chlorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-2-yl]acetic acidnon-polymer342.83Chemie (R2D)
3waterwater18.047Chemie (HOH)
Sequence modifications
A, B: 49 - 212 (UniProt: A0A0U2U525)
PDBExternal DatabaseDetails
Met 36-initiating methionine
Ala 37-expression tag
His 38-expression tag
His 39-expression tag
His 40-expression tag
His 41-expression tag
His 42-expression tag
His 43-expression tag
Leu 44-expression tag
Val 45-expression tag
Pro 46-expression tag
Arg 47-expression tag
Gly 48-expression tag
Ser 49Ala 49conflict
Ser 56Cys 56conflict
Asp 139Phe 139conflict
His 185Phe 185conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight39030.4
Non-Polymers*Number of molecules3
Total formula weight1028.4
All*Total formula weight40058.8
*Water molecules are not included.

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon