6VAF
Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fanconi anemia, complementation group I | polymer | 1328 | 149566.0 | 1 | UniProt (B7ZMF2) Pfam (PF14674) Pfam (PF14675) Pfam (PF14679) Pfam (PF14676) Pfam (PF14680) Pfam (PF14677) Pfam (PF14678) UniProt (by SIFTS) (Q9NVI1) In PDB | Homo sapiens (Human) | |
| 2 | B | Fanconi anemia group D2 protein | polymer | 1451 | 164314.5 | 1 | UniProt (Q9BXW9) Pfam (PF14631) In PDB | Homo sapiens (Human) | Protein FACD2 |
| 3 | D | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG48) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
| 4 | S | DNA (29-MER) | polymer | 29 | 8951.7 | 1 | Homo sapiens | ||
| 5 | T | DNA (29-MER) | polymer | 29 | 8880.7 | 1 | Homo sapiens |
Sequence modifications
A: 1 - 1328 (UniProt: B7ZMF2)
B: 1 - 1451 (UniProt: Q9BXW9)
| PDB | External Database | Details |
|---|---|---|
| Val 136 | Ala 136 | conflict |
| Asn 476 | Ser 476 | conflict |
| Glu 638 | Lys 638 | conflict |
| Gln 657 | Lys 657 | conflict |
| Leu 877 | Ile 877 | conflict |
| Val 1235 | Ala 1235 | conflict |
| Ser 1274 | Asn 1274 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 654 | His 654 | conflict |
| Asn 693 | Asp 693 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 340289.9 | |
| All* | Total formula weight | 340289.9 |
