6V7E

Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Arginase-1	polymer	322	34779.9	6	UniProt (P05089) Pfam (PF00491) In PDB	Homo sapiens (Human)	Liver-type arginase,Type I arginase
2	A, B, C, D, E...	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
3	A, B, C, D, E...	3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide	non-polymer		287.1	6	Chemie (QRA)
4		water	water		18.0	1111	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	208679.3
Non-Polymers*	Number of molecules	18
	Total formula weight	2382.1
All*	Total formula weight	211061.4

*Water molecules are not included.