6V3F

Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	NPC1-like intracellular cholesterol transporter 1	polymer	1336	147640.2	1	UniProt (Q6T3U3) Pfam (PF16414) Pfam (PF22314) Pfam (PF12349) Pfam (PF02460) In PDB	Rattus norvegicus (Rat)	Niemann-Pick C1-like protein 1
2	B, C, D, E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
4	A	CHOLESTEROL	non-polymer		386.7	1	Chemie (CLR)

Sequence modifications

A: 21 - 1331 (UniProt: Q6T3U3)

PDB	External Database	Details
Glu 1332	-	expression tag
Asn 1333	-	expression tag
Leu 1334	-	expression tag
Tyr 1335	-	expression tag
Phe 1336	-	expression tag
Gln 1337	-	expression tag
Gly 1338	-	expression tag
Asp 1339	-	expression tag
Tyr 1340	-	expression tag
Lys 1341	-	expression tag
Asp 1342	-	expression tag
Asp 1343	-	expression tag
Asp 1344	-	expression tag
Asp 1345	-	expression tag
Lys 1346	-	expression tag
His 1347	-	expression tag
His 1348	-	expression tag
His 1349	-	expression tag
His 1350	-	expression tag
His 1351	-	expression tag
His 1352	-	expression tag
His 1353	-	expression tag
His 1354	-	expression tag
His 1355	-	expression tag
His 1356	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	147640.2
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	11
	Total formula weight	2598.7
All*	Total formula weight	151936.5

*Water molecules are not included.