6V1B
Crystal structure of the bromodomain of human BRD9 bound to I-BRD9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 2 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 2 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | D, E (A, B) | N'-[1,1-bis(oxidanylidene)thian-4-yl]-5-ethyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide | non-polymer | 497.6 | 2 | Chemie (H1B) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 250 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28499.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1057.2 | |
| All* | Total formula weight | 29556.7 |
