6V1B
Crystal structure of the bromodomain of human BRD9 bound to I-BRD9
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | SER174 |
| A | ILE177 |
| A | LYS178 |
| A | PRO180 |
| A | HOH446 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue H1B A 302 |
| Chain | Residue |
| A | TYR215 |
| A | ASN216 |
| A | ARG217 |
| A | THR220 |
| A | TYR222 |
| A | LYS239 |
| A | GLU240 |
| A | HOH416 |
| A | HOH485 |
| A | PHE160 |
| A | PHE161 |
| A | VAL165 |
| A | ILE169 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue H1B B 301 |
| Chain | Residue |
| B | PHE160 |
| B | PHE161 |
| B | VAL165 |
| B | ILE169 |
| B | TYR215 |
| B | ASN216 |
| B | ARG217 |
| B | THR220 |
| B | TYR222 |
| B | HOH408 |
| B | HOH457 |
| B | HOH463 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
