6V17
Crystal structure of the bromodomain of human BRD7 bound to I-BRD9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 7 | polymer | 123 | 14394.6 | 2 | UniProt (Q9NPI1) Pfam (PF00439) | Homo sapiens (Human) | 75 kDa bromodomain protein,Protein CELTIX-1 |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D, E (A, B) | N'-[1,1-bis(oxidanylidene)thian-4-yl]-5-ethyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide | non-polymer | 497.6 | 2 | Chemie (H1B) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 250 (UniProt: Q9NPI1)
| PDB | External Database | Details |
|---|---|---|
| Glu 128 | - | expression tag |
| Ser 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28789.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1030.6 | |
| All* | Total formula weight | 29819.8 |
