6V17
Crystal structure of the bromodomain of human BRD7 bound to I-BRD9
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 301 |
| Chain | Residue |
| A | SER227 |
| A | LYS230 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue H1B A 302 |
| Chain | Residue |
| A | LYS212 |
| A | THR215 |
| A | TYR217 |
| A | ASP249 |
| A | HOH401 |
| B | SER153 |
| B | ALA154 |
| A | PHE155 |
| A | PHE156 |
| A | VAL160 |
| A | ILE164 |
| A | ALA207 |
| A | TYR210 |
| A | ASN211 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue H1B B 301 |
| Chain | Residue |
| A | PRO152 |
| A | SER153 |
| B | PHE155 |
| B | PHE156 |
| B | ILE164 |
| B | ALA165 |
| B | ASN211 |
| B | LYS212 |
| B | THR215 |
| B | TYR217 |
| B | ASP249 |
| B | HOH401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS241 | |
| B | LYS186 | |
| B | LYS197 | |
| B | LYS201 | |
| B | LYS212 | |
| B | LYS241 | |
| A | LYS186 | |
| A | LYS197 | |
| A | LYS201 | |
| A | LYS212 |
