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6V0O

PRMT5 bound to the PBM peptide from pICln

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein arginine N-methyltransferase 5polymer63772766.71UniProt (O14744)
Pfam (PF17285)
Pfam (PF05185)
Pfam (PF17286)
Homo sapiens (Human)72 kDa ICln-binding protein,Histone-arginine N-methyltransferase PRMT5,Jak-binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB1Hs
2B
(B)
Methylosome protein 50polymer34236723.21UniProt (Q9BQA1)
Pfam (PF00400)
Homo sapiens (Human)MEP-50,Androgen receptor cofactor p44,WD repeat-containing protein 77,p44/Mep50
3C
(D)
PBM peptidepolymer131404.41UniProt (by SIFTS) (P54105)Homo sapiens
4D
(A)
SINEFUNGINnon-polymer381.41Chemie (SFG)
5E
(A)
ACETYL GROUPnon-polymer44.11Chemie (ACE)
Sequence modifications
B: 2 - 342 (UniProt: Q9BQA1)
PDBExternal DatabaseDetails
Pro 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight110894.2
Non-Polymers*Number of molecules2
Total formula weight425.4
All*Total formula weight111319.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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