6UZK
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Krev interaction trapped protein 1 | polymer | 322 | 37372.3 | 1 | UniProt (O00522) Pfam (PF00373) In PDB | Homo sapiens (Human) | Krev interaction trapped 1,Cerebral cavernous malformations 1 protein |
2 | B | Ras-related protein Rap-1b | polymer | 167 | 19020.5 | 1 | UniProt (P61224) Pfam (PF00071) In PDB | Homo sapiens (Human) | GTP-binding protein smg p21B |
3 | A | 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde | non-polymer | 202.2 | 1 | Chemie (QMA) | |||
4 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | B | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
6 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 417 - 736 (UniProt: O00522)
PDB | External Database | Details |
---|---|---|
Gly 415 | - | expression tag |
Ala 416 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56392.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 748.7 | |
All* | Total formula weight | 57141.6 |