6UZA
Cryo-EM structure of human TRPC6 in complex with antagonist AM-1473
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Short transient receptor potential channel 6 | polymer | 847 | 97202.9 | 4 | UniProt (Q9Y210) Pfam (PF12796) Pfam (PF08344) Pfam (PF00520) Pfam (PF08016) | Homo sapiens (Human) | TrpC6,Transient receptor protein 6,TRP-6 |
| 2 | E, L, Q, V (A, B, C, D) | 4-({(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl}oxy)benzonitrile | non-polymer | 333.4 | 4 | Chemie (R0G) | |||
| 3 | F, M, R, W (A, B, C, D) | 2-[[(2~{S})-2-decanoyloxypropoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium | non-polymer | 396.5 | 4 | Chemie (S9Y) | |||
| 4 | G, I, N, S (A, B, C) | [(2~{S})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-octanoyloxy-propan-2-yl] octadecanoate | non-polymer | 607.8 | 4 | Chemie (SBJ) | |||
| 5 | H, J, K, O, P... (A, B, C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 8 | Chemie (Y01) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 388811.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 9244.6 | |
| All* | Total formula weight | 398056.1 |
