6UPR
Crystal Structure of GTPase Domain of Human Septin 2 / Septin 8 Heterocomplex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Septin-2 | polymer | 274 | 31691.3 | 1 | UniProt (Q15019) Pfam (PF00735) | Homo sapiens (Human) | Neural precursor cell expressed developmentally down-regulated protein 5,NEDD-5 |
| 2 | B (B) | Septin-8 | polymer | 292 | 33630.1 | 1 | UniProt (Q92599) Pfam (PF00735) | Homo sapiens (Human) | |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 36 - 308 (UniProt: Q15019)
B: 36 - 311 (UniProt: Q92599)
| PDB | External Database | Details |
|---|---|---|
| Met 35 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | initiating methionine |
| Gly 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Ser 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Gln 31 | - | expression tag |
| Asp 32 | - | expression tag |
| Pro 33 | - | expression tag |
| Asn 34 | - | expression tag |
| Ser 35 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65321.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 990.7 | |
| All* | Total formula weight | 66312.1 |
