6UP5
Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Triosephosphate isomerase | polymer | 252 | 26983.7 | 2 | UniProt (P60174) Pfam (PF00121) | Homo sapiens (Human) | TIM,Methylglyoxal synthase,Triose-phosphate isomerase |
| 2 | C, D, H (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | E, F, I (A, B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 3 | Chemie (IPA) | |||
| 4 | G (B) | 2-PHOSPHOGLYCOLIC ACID | non-polymer | 156.0 | 1 | Chemie (PGA) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 393 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 248 (UniProt: P60174)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53967.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 612.6 | |
| All* | Total formula weight | 54580.1 |
