6U6Z
Human SAMHD1 bound to deoxyribo(TG*TTCA)-oligonucleotide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | polymer | 535 | 61780.4 | 4 | UniProt (Q9Y3Z3) Pfam (PF01966) In PDB | Homo sapiens (Human) | dNTPase,Dendritic cell-derived IFNG-induced protein,DCIP,Monocyte protein 5,MOP-5,SAM domain and HD domain-containing protein 1,hSAMHD1 |
2 | E, F, H, G | DNA polymer TG(PST)TCA | polymer | 6 | 1815.3 | 4 | synthetic construct | ||
3 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 116 - 626 (UniProt: Q9Y3Z3)
PDB | External Database | Details |
---|---|---|
Met 92 | - | initiating methionine |
Trp 93 | - | expression tag |
Ser 94 | - | expression tag |
His 95 | - | expression tag |
Pro 96 | - | expression tag |
Gln 97 | - | expression tag |
Phe 98 | - | expression tag |
Glu 99 | - | expression tag |
Lys 100 | - | expression tag |
Gly 101 | - | expression tag |
Ser 102 | - | expression tag |
Gly 103 | - | expression tag |
Ser 104 | - | expression tag |
Glu 105 | - | expression tag |
Asn 106 | - | expression tag |
Leu 107 | - | expression tag |
Tyr 108 | - | expression tag |
Phe 109 | - | expression tag |
Gln 110 | - | expression tag |
Gly 111 | - | expression tag |
Gly 112 | - | expression tag |
Gly 113 | - | expression tag |
Gly 114 | - | expression tag |
Gly 115 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 254382.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 261.6 | |
All* | Total formula weight | 254644.5 |