6U16
Human thymine DNA glycosylase N140A mutant bound to DNA with 5-carboxyl-dC substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G/T mismatch-specific thymine DNA glycosylase | polymer | 227 | 25832.0 | 1 | UniProt (Q13569) Pfam (PF03167) | Homo sapiens (Human) | Thymine-DNA glycosylase,hTDG |
| 2 | B (C) | DNA (28-MER) | polymer | 28 | 8646.6 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (28-MER) | polymer | 28 | 8610.5 | 1 | synthetic construct | ||
| 4 | D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H, I (A, C, D) | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence modifications
A: 82 - 308 (UniProt: Q13569)
| PDB | External Database | Details |
|---|---|---|
| Ala 140 | Asn 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43089.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 43275.3 |
