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6TRW

Crystal structure of DPP8 in complex with the EIL peptide (SLRFLFEGQRIADNH)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CDipeptidyl peptidase 8polymer903103886.83UniProt (Q6V1X1)
Pfam (PF19520)
Pfam (PF00930)
Pfam (PF00326)
In PDB
Homo sapiens (Human)DP8,Dipeptidyl peptidase IV-related protein 1,DPRP-1,Dipeptidyl peptidase VIII,DPP VIII,Prolyl dipeptidase DPP8
2D, E, FSER-LEU-ARG-PHE-LEU-PHE-GLU-GLY-GLN-ARGpolymer151806.03UniProt (by SIFTS) (P63165)
In PDB
Homo sapiens
3A, B, CSODIUM IONnon-polymer23.03Chemie (NA)
4waterwater18.033Chemie (HOH)
Sequence modifications
A, B, C: 1 - 898 (UniProt: Q6V1X1)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight317078.5
Non-Polymers*Number of molecules3
Total formula weight69.0
All*Total formula weight317147.4
*Water molecules are not included.

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PDB entries from 2024-07-17

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