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6TRW

Crystal structure of DPP8 in complex with the EIL peptide (SLRFLFEGQRIADNH)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Dipeptidyl peptidase 8polymer903103886.83UniProt (Q6V1X1)
Pfam (PF19520)
Pfam (PF00930)
Pfam (PF00326)
Homo sapiens (Human)DP8,Dipeptidyl peptidase IV-related protein 1,DPRP-1,Dipeptidyl peptidase VIII,DPP VIII,Prolyl dipeptidase DPP8
2D, E, F
(D, E, F)
SER-LEU-ARG-PHE-LEU-PHE-GLU-GLY-GLN-ARGpolymer151806.03UniProt (by SIFTS) (P63165)Homo sapiens
3G, H, I
(A, B, C)
SODIUM IONnon-polymer23.03Chemie (NA)
4J, K, L, M, N...
(A, B, C, D, E...)
waterwater18.033Chemie (HOH)
Sequence modifications
A, B, C: 1 - 898 (UniProt: Q6V1X1)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight317078.5
Non-Polymers*Number of molecules3
Total formula weight69.0
All*Total formula weight317147.4
*Water molecules are not included.

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PDB entries from 2025-07-16

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