6TQS
The crystal structure of the MSP domain of human MOSPD2 in complex with the conventional FFAT motif of ORP1.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Motile sperm domain-containing protein 2 | polymer | 216 | 24268.6 | 6 | UniProt (Q8NHP6) Pfam (PF00635) In PDB | Homo sapiens (Human) | |
2 | G, H, I, J, K | Oxysterol-binding protein-related protein 1 | polymer | 21 | 2323.4 | 5 | UniProt (Q9BXW6) In PDB | Homo sapiens | OSBP-related protein 1 |
3 | A, B, C | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
4 | F, A, B, C, D... | trifluoroacetic acid | non-polymer | 114.0 | 6 | Chemie (TFA) | |||
5 | E, F, A, C | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
6 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
7 | C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
8 | F | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
9 | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 282 - 490 (UniProt: Q8NHP6)
G, H, I, J, K: 469 - 485 (UniProt: Q9BXW6)
PDB | External Database | Details |
---|---|---|
Met 281 | - | initiating methionine |
His 491 | - | expression tag |
His 492 | - | expression tag |
His 493 | - | expression tag |
His 494 | - | expression tag |
His 495 | - | expression tag |
His 496 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 465 | - | cloning artifact |
Ala 466 | - | cloning artifact |
Met 467 | - | cloning artifact |
Arg 468 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 157228.7 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 2004.8 | |
All* | Total formula weight | 159233.5 |