6TQS

The crystal structure of the MSP domain of human MOSPD2 in complex with the conventional FFAT motif of ORP1.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Motile sperm domain-containing protein 2	polymer	216	24268.6	6	UniProt (Q8NHP6) Pfam (PF00635)	Homo sapiens (Human)
2	G, H, I, J, K (G, H, I, J, K)	Oxysterol-binding protein-related protein 1	polymer	21	2323.4	5	UniProt (Q9BXW6)	Homo sapiens	OSBP-related protein 1
3	L, M, O, S, T (A, B, C)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
4	BA, N, R, U, X... (F, A, B, C, D...)	trifluoroacetic acid	non-polymer		114.0	6	Chemie (TFA)
5	AA, DA, P, W, Z (E, F, A, C)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
6	Q (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	V (C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
8	CA (F)	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
9	EA, FA, GA, HA, IA... (A, B, C, D, E...)	water	water		18.0	270	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 282 - 490 (UniProt: Q8NHP6)

PDB	External Database	Details
Met 281	-	initiating methionine
His 491	-	expression tag
His 492	-	expression tag
His 493	-	expression tag
His 494	-	expression tag
His 495	-	expression tag
His 496	-	expression tag

G, H, I, J, K: 469 - 485 (UniProt: Q9BXW6)

PDB	External Database	Details
Gly 465	-	cloning artifact
Ala 466	-	cloning artifact
Met 467	-	cloning artifact
Arg 468	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	157228.7
Non-Polymers*	Number of molecules	19
	Total formula weight	2004.8
All*	Total formula weight	159233.5

*Water molecules are not included.