6TQK

Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Uromodulin	polymer	563	61498.8	3	UniProt (P07911) Pfam (PF12947) Pfam (PF07645) Pfam (PF00100) In PDB	Homo sapiens (Human)	Tamm-Horsfall urinary glycoprotein,THP
2	D, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	E, G	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1479.3	2	In PDB GlyTouCan (G24420RT)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	184496.4
Branched	Number of molecules	4
	Total formula weight	3807.5
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	188746.4

*Water molecules are not included.