6TLQ
ROR(gamma)t ligand binding domain in complex with cholesterol and allosteric ligand Glenmark
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nuclear receptor ROR-gamma | polymer | 263 | 30514.2 | 1 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
2 | A | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
3 | A | 4-[1-[2,6-bis(chloranyl)phenyl]carbonyl-5-methyl-thieno[3,2-c]pyrazol-3-yl]benzoic acid | non-polymer | 431.3 | 1 | Chemie (MJE) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
PDB | External Database | Details |
---|---|---|
Gly 245 | - | expression tag |
Ser 246 | - | expression tag |
Ser 247 | - | expression tag |
His 248 | - | expression tag |
His 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
Ser 254 | - | expression tag |
Ser 255 | - | expression tag |
Gly 256 | - | expression tag |
Leu 257 | - | expression tag |
Val 258 | - | expression tag |
Pro 259 | - | expression tag |
Arg 260 | - | expression tag |
Gly 261 | - | expression tag |
Ser 262 | - | expression tag |
His 263 | - | expression tag |
Met 264 | - | expression tag |
His 455 | Cys 455 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 30514.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1094.2 | |
All* | Total formula weight | 31608.4 |